Goiter needs nursing. It is thyroid gland hypertrophy, important organ of endocrine system produces hormones for metabolism, poly organ normal function including blood chemistry, hemodynamics & erythropoiesis. Arising out of  Iodine deficiency and or life style, jointly or severally. Rarely cancer. Hypothalamus signals pituitary gland to produce thyroid-stimulating hormone (TSH), which regulates hormone production. TSH uptake and\or efficient conversion is the pathophysiology. Current standard medication for such pathophysiology  being long period ‘hormone replacement therapy’ (HRT). No prophylaxis; no synergic medicaments; no functional food. There are several natural sources (a) Star Anise -Illicium Verumtree (b) Cinnamon Bark - Cinnamon verum\cassia (c) Fruit & flower of  Myristica  fragrans are rich in (i) caffeic (ii) cinnamic acids; no conflicting and or confounding co-moieties; have abundant availability; historical (non-goiter specific) home use worldwide & non-toxic. Study indicates the theoretical-computational interaction of TSH with compound (i) & (ii). RESULT :   Binding affinity is of the order -5 kcal/Mol for either with a minimum of 4 ‘H’ bonds at ~ 2 Å distance and a stable-high ‘inhibition constant’ of   >180µm. Thus, compound (i) & (ii) present likeness, compatibility with TSH as Drug Discovery candidates at molecular level and also as ‘synergic’ with TSH.  Medicinal plant products  ‘A-B-C’ posits the immediate possibility of use as ‘Functional Foods’ targeting TSH uptake and\or efficient conversion. Goiter is chronic and is treated as  out-patient malady.  Caffeic & cinnamic acids rich functional foods are (A) prophylactic  (B) effective tools in the hands of the nurses. Paradigm shift in concept.