Purpose: The study assessed patient’s perception of quality and satisfaction of with postoperative nursing care in surgical wards in University of Benin Teaching Hospital, Edo state. Methods A descriptive cross-sectional survey was used, among 184 participants selected using simple random technique. A researcher developed and validated questionnaire was used as instrument of data collection. Data collected was analyse using descriptive statistics while hypothesis tested using multiple logistic regression at 5% level of significant. Data analysis was done with SPSS version 28. Findings Results showed that 125(89.9%) had a positive perception toward quality nursing care, 122(87.8%) are satisfied, while 17(12.2%) are dissatisfied with postoperative nursing care. Major factors that contributed to patient satisfaction with postoperative nursing care were availability of family and support persons and maintenance of safety and comfort with a mean of 3.72 and 3.68 respectively, while the least factor was staff attitude and teamwork with a mean of 3.51. Female (OR = 4.90, 95% CI: 0.23–3.54, p = 0.479), Age 31–40 years (OR = 7.03, 95% CI: 0.06–8.28, p = 0.298) Length of Hospital Stay Less than 7 days (OR = 4.69, 95% CI: 1.13–3.11, p = 4.174) have higher odds of satisfaction with care, similarity, Female (OR = 2.31, 95% CI: 0.074–8.599, p = 0.851): 31–40 years (OR = 4.06, 95% CI: 0.108–2.822, p = 0.476), Length of Hospital Stay Less than 7 days (OR = 4.16, 95% CI: 0.04–0.66, p = 0.011): higher odds of a positive